Oral Solids

We are experts in the manufacturing of high-quality oral solid tablets, combining cutting-edge technology with decades of experience.
Our advanced facility is equipped for precision-driven granulation, compression, and film coating, including semi-continuous processes that enhance efficiency and product consistency. With a team of over 330 highly skilled professionals and one of Japan’s largest cold storage warehouses, our Kawagoe facility ensures seamless production, strict quality control, and compliance with global pharmaceutical regulations.

Uncoated Tablets

Uncoated tablets are the most fundamental type of oral solid dosage form, consisting of compressed active and inactive ingredients without an external coating. They are designed for immediate release, allowing rapid disintegration and absorption in the digestive system. Due to their simple formulation and production process, uncoated tablets are widely used across various therapeutic areas.

  • Cost-effective and easy to manufacture, making them an ideal choice for high-volume production.
  • Fast disintegration and absorption in the stomach, ensuring quick therapeutic effects.
  • Suitable for a wide range of active pharmaceutical ingredients (APIs), from pain relievers to antibiotics and vitamins.
  • Flexible formulation options, allowing for different sizes, shapes, and scoring for dose adjustments.

Film-Coated Tablets

Film-coated tablets are solid dosage forms covered with a thin layer of polymer coating, which improves stability, enhances taste masking, and facilitates swallowing. The coating can be either aqueous or solvent-based, tailored to protect the active ingredient and optimize drug release.

  • Aqueous or solvent-based coating options provide flexibility in formulation to meet different stability requirements.
  • Protects active ingredients from moisture and oxidation, extending shelf life and ensuring potency.
  • Improves patient compliance with a smoother texture, reducing swallowing discomfort.
  • Enhances appearance with uniform color and gloss, improving product differentiation and branding.

Orally Dissolving Tablets (ODT)

Orally dissolving tablets (ODTs) are designed to disintegrate quickly on the tongue without the need for water, offering a convenient alternative to traditional tablets. They are especially beneficial for patients who have difficulty swallowing, such as pediatric, geriatric, or dysphagic populations.

  • Ideal for patients with difficulty swallowing, reducing the risk of choking and improving adherence.
  • Ensures fast drug absorption through the oral mucosa, bypassing first-pass metabolism for quicker onset of action.
  • Enhances patient adherence, particularly in children and the elderly who struggle with conventional tablets.
  • Portable and convenient, making them a preferred choice for on-the-go medication.

Multi-Layer Tablets

Multi-layer tablets are advanced oral solid dosage forms that consist of two or more layers, allowing for complex drug delivery mechanisms. They are used for combination therapies or to achieve controlled and sequential drug release.

  • Enables sequential or dual-action drug delivery, allowing different APIs to be released at specific times.
  • Improves formulation stability by separating incompatible ingredients, preventing premature drug interactions.
  • Supports extended or targeted release profiles, optimizing therapeutic efficacy and reducing dosing frequency.
  • Ideal for combination therapies, reducing pill burden by incorporating multiple drugs into a single tablet.
image of our facility in Kawagoe

Our Network for Oral Solids

Our site in Kawagoe, Japan, specializes in Uncoated Tablets, Film-coated Tablets, Orally Dissolving Tablets (ODT) and Multi-Layer Tablets.

  • Technology: Granulation and compression of tablets, Uncoated / Film-caoted / Orrally Dissolving Tablets (ODT) / Multi-layer Tablets
  • Tableting: 2 billion per year
  • Packaging: 2 billion per year

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